In addition to the space program, it is also responsible for long-term civilian and military aerospace research. Since February 2006 NASA's self-described mission statement is to "pioneer the future in space exploration, scientific discovery, and aeronautics research."

NASA's motto is: "For the benefit of all". The motto of NASA's Office of Education is: Shaping the Future: Launching New Endeavors to Inspire the Next Generation of Explorers.